Unwind. It's a warm, friendly environment with slot machines. 1. Our New Mexico casino is open 24/7 daily. A warm and friendly environment with slot machines at the Main Casino. No Smoking Facility. Must be 21+. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. Learn More. Excite. Saturdays in. Seadust Cancun Family Resort · 6, reviews. Upcoming Events. Win. Indulge. #2 Best Value of 24 Mexico. at Isleta Resort & Casino. Sky City Casino is open 24 hours daily. Colorful bingo cards and round bingo balls w/numbers. #1 Best Value of 24 Mexico Casino Hotels ; 2. These casinos and gaming sites are owned by 14 New Mexico. With three live entertainment venues, you'll find something around every corner. The Pyramid Cancun · 4, reviews. The Travel center includes a casino area with 45 slot machines. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. . DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. Open 24 hours, 7 days a week! What's happening. Swirls of Cash. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties.