Just blocks from Canalside, HarborCenter, the Cobblestone District, KeyBank Center, Coca-Cola® Field, the Theatre District, Larkin Square and all other. Come here to have fun! The 2 established casinos in Buffalo (Buffalo Creek Seneca Casino and Buffalo Casino & Raceway Hamburg) naturally have an array of slot machines on top of. Akwesasne Mohawk Casino, Hogansburg · State Route 37 ; Buffalo Raceway Hamburg Gaming, Hamburg · South Park Avenue ; Casino Empire City Yonkers. Top 10 Best Casinos Near Buffalo, New York · Seneca Buffalo Creek Casino · Seneca Niagara Resort & Casino · Hamburg Fairgrounds · Casino Niagara · Buffalo Creek. Seneca Buffalo Creek Casino is a Native American casino in Buffalo, New York and is open daily 24 hours. Complete casino information including address, telephone number, map, gaming tables, slot machines. Enjoy drinks and cocktails at choice of bars. If you're seeking the thrill of the game, Seneca Niagara is the place for you. Buffalo Creek Casino in Buffalo, New York. Seneca Buffalo Creek Casino in Buffalo, NY features over slot machines, table games, great restaurants, and a laidback vibe. Visit Seneca Buffalo Creek Casino for thrilling gaming, sports betting and great restaurants. - See traveler reviews, candid photos. Seneca Niagara Resort & Casino: Probably the best casino + hotel choice in the Niagara Falls area. . We offer over 80 tables of live-action gaming plus more than 2, slot machines. The casino's 67, square foot gaming space.